around one million people are thought to malaria kills scientists they are closer believe to able to change the DNA of wild mosquitoes, to combat malaria.In the laboratory they made a gene from a handful of mosquitoes in the majority of the population in only a few generations, distributed according to a report in nature.
If the right conditions made can be spread then hope researchers to reduce the number of malaria cases.
Other academics have described the study as an "important step".
The World Health Organization estimates that malaria causes nearly one million deaths in the year 2008.
Diffusion resistanceResearch groups have already interrupting "malaria resistant mosquitoes" with techniques such as the introduction of genes the malaria parasite development created.
The research, but has a major challenge - always these genes to spread of genetically modified mosquitoes to the vast number of wild insects around the world.
Unless the gene of the mosquito is an advantage, the gene will probably disappear.
Scientists at Imperial College in London and the University of Washington in Seattle, believe that they have found a solution.
Further one million deaths - read with the main story largely preventable and curable 2008 caused mainly African ChildrenAbout 1,500 people back in the United Kingdom malaria of each YearOnly 12% of serious IllSymptoms can be up to relax a year, to AppearThey inserted a gene into mosquito DNA, looking after its own interests very well is - called a homing endonuclease SceI.The gene is an enzyme that cuts the DNA in two. The cell repair machines then used the gene as a template when the repair of the cut.
This is the homing endonuclease gene copies.
This is done so that all the sperm from a male mosquito carrying the gene produced.
All of his descendants have the gene. The process is then repeated, so that the offspring of descendants of the gene and so on.
In laboratory experiments the gene half spread the caged mosquitoes in 12 generations.
Against malariaProfessor Andrea Crisanti, at the Faculty of life sciences at Imperial College in London, said: "this is an exciting technological development, one that hopefully paves the way for solutions to many global health problems."
"I was very skeptical at the beginning and thought it probably would not work, but the results are so encouraging that I begin to change to my mind."
He said the idea had in principle as and was now working to spread other genes in the same way.
He believes it may be possible to introduce genes that stop target animals instead of people, the mosquito the parasites from the multiplication in the insect or produce any male descendants, that is do not transmit malaria.
Professor Janet Hemingway, from the Liverpool said school of tropical medicine, the work was a "thrilling breakthrough".
They warned that the technology was still used in some way against the wild mosquitoes, and there were social issues surrounding the acceptability of the use of GM technology.
"However, this is an important step forward a technology that beneficial drive genes by mosquito populations of relatively small releases used in a low-cost format can be", she added.
Dr. Yeya Touré, by the World Health Organisation, said: "This research is very important for the driving of a foreign gene into a mosquito population." "But given the fact that it has been the model in a laboratory cage, is the need to further study before it could be used as genetic control strategy."
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